Micro- And Nano-Transport Of Biomolecules by Bakewell

By Bakewell

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Com/graduates. com 56 4. Basic micro- and nano-transport Micro- and Nano-Transport of Biomolecules approximation the screened free charge is assumed to be practically negligible. 12) introduces a slightly more compact notation for partial derivatives. Poisson’s and Laplace’s equations are solved by applying Boundary Conditions (BCs) for the potential and the electric field. There are two types of BCs, Dirichlet and Neumann, and these are described with examples in the next chapter. As discussed in previous chapters many biomolecules, such nucleic acids or proteins, are responsive to electric fields and laboratory electrophoresis equipment used today testifies to this property.

10) and reveals two interesting features. First, it shows the conductivity parameters dominate at low frequencies, and the permittivities at high frequencies, Re{ f CM (Z )} ­(V p  V m ) (V p  2V m ), W MW Z  1 ½ ° ° ® ¾ °(V  V ) (V  2V ) , W Z !! 11) H pV m , the real part of the Clausius-Mossotti function is shown to be frequency independent. com 39 3. 12), positive DEP occurs when Re{ fCM (Z )} ! 0 , the direction of the force F is governed by 2 d E / dx , so the particle moves towards the region of maximum electric field intensity.

A) np particles with permittivity Hp* and spherical volume, V enclosed in volume, VT (b) Equivalent sphere with effective permittivity Heff* and volume VT. 4 Concluding remarks This chapter has described the structure and biological function of biomolecules and introduced their electrical properties as they behave in aqueous solution. Concepts, such as double-layer, dielectric polarization, and bioparticle will be important for subsequent chapters that focus on biomolecule transport, particularly using electric fields.

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