FNA Cytology in the Diagnosis of Lymphoma (Monographs in by Lambert Skoog, Edneia Tani

By Lambert Skoog, Edneia Tani

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Additional resources for FNA Cytology in the Diagnosis of Lymphoma (Monographs in Clinical Cytology Vol 18)

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The centrocytes vary in size between different tumors but the individual cell has a rounded nucleus with a narrow rim of pale blue cytoplasm (MGG). The nucleus is characteristically cleaved, sometimes to the extent that it looks bi-lobed. Nucleoli are rarely seen. The second tumor cell, the centroblast, is medium sized to large and has a round nucleus with a reticular chromatin pattern. One to several usually small nucleoli can be observed and they are often located at the nuclear membrane (fig.

5 Shimoyama M: Diagnostic criteria and classification of clinical subtypes of adult T-cell leukaemia-lymphoma: a report from the Lymphoma Study Group. Br J Haematol 1991; 79:428–437. 6 Oshima K, Tani E, Masuda Y, Skoog L, Kikuchi M: Fine needle aspiration cytology of high grade T-cell lymphomas in human T-lymphotropic virus type 1 carriers. Cytopathology 1992;3:365–372. 7 Tong GX, Hernandez O, Yee HT, et al: Human T-lymphotropic virus type-1 related adult T-cell leukemia/lymphoma presenting as a parotid mass diagnosed by fine-needle aspiration biopsy.

Lyon, IARC Press, 2001, pp 135–137. 10 Thieblemont C, Felman P, Callet-Bauchu E, et al: Splenic marginal zone-lymphoma: a distinct clinical and pathological entity. Lancet Oncol 2003;4:95–103. 11 Chacon JI, Mollejo M, Munoz E, et al: Splenic marginal zone lymphoma: clinical characteristics and prognostic factors in a series of 60 patients. Blood 2002;100:1648–1654. 12 Matsushima AY, Hamele-Bena D, Osborne BM: Fine-needle aspiration biopsy findings in marginal zone B-cell lymphoma. Diagn Cytopathol 1999;20:190–198.

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