Animal Models of Behavior Genetics by Jonathan C. Gewirtz, Yong-Kyu Kim

By Jonathan C. Gewirtz, Yong-Kyu Kim

This stimulating research experiences the wide strength of animal types to foster a deeper realizing of human pathology, improve connections among genetic and behavioral stories, and improve more suitable remedies for psychological problems. Widely-studied and lesser-used species are tested in types that trap gains alongside the continuum of normative and pathological habit. The types spotlight genetic factors of middle good points, or endophenotypes, of developmental, internalizing, and externalizing issues, in addition to dementia. professional members deal with questions starting from how appropriate species are selected for examine to the prices and merits of utilizing inbred as opposed to outbred lines, and the results of housing surroundings on topic animals. higher concerns addressed comprise the best way to review the applicability of animal behavioral versions to the human and the way those types can harness rising molecular applied sciences to additional our realizing of the genetic foundation of psychological illness.

Included within the coverage:

  • Mating and struggling with in Drosophila.
  • Attachment and social bonding.
  • Impulsivity in rodents and humans.
  • Animal types of cognitive decline.
  • Animal versions of social cognition.
  • Future instructions for animal types in behavioral genetics.

A special map of the place this evolving box is headed, Animal types of habit Genetics indicates geneticists, molecular biologists, and cognitive neuroscientists paths past validated recommendations towards a extra an expert and collaborative future.

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Extra resources for Animal Models of Behavior Genetics

Sample text

Fruitless splicing specifies male courtship behavior in Drosophila. Cell, 121, 785–794. , Jan, Y. , Quinn, W. , & Benzer, S. (1976). dunce, a mutant of Drosophila deficient in learning. Proceedings of the National Academy of Sciences of the United States of America, 73, 1684–1688. Edwards, A. , Ayroles, J. , Stone, E. , Carbone, M. , Lyman, R. , & Mackay, T. F. (2009). A transcriptional network associated with natural variation in Drosophila aggressive behavior. Genome Biology, 10, R76. , & Griffith, L.

Griffith, L. C. (2008). Courtship initiation is stimulated by acoustic signals in Drosophila melanogaster. PLoS ONE, 3, e3246. , Manoli, D. , Ahmed, O. , et al. (2013). Genetic and neural mechanisms that inhibit Drosophila from mating with other species. Cell, 154, 89–102. 28 D. Yamamoto Ferveur, J. F. (1997). The pheromonal role of cuticular hydrocarbons in Drosophila melanogaster. Bioessays, 19, 353–358. Ferveur, J. , & Greenspan, R. J. (1998). Courtship behavior of brain mosaics in Drosophila.

2008). Sex-specific control tuning of the pattern generator for courtship song in Drosophila. Cell, 133, 354–363. , Weinstein, A. , Pacheco, D. , & Murthy, M. (2014). Dynamic sensory cues shape song structure in Drosophila. Nature, 507, 233–237. Dalton, J. , Fear, J. , Baker, B. , McIntyre, L. , & Arbeitman, M. N. (2013). Male-specific fruitless isoforms have different regulatory roles conferred by distinct zinc finger DNA binding domains. BMC Genomics, 14, 659. , & Dickson, B. J. (2005). fruitless splicing specifies male courtship behavior in Drosophila.

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