Activins and Inhibins by Gerald Litwack

By Gerald Litwack

First released in 1943, Vitamins and Hormones is the longest-running serial released via educational Press. The Editorial Board now displays services within the box of hormone motion, nutrition motion, X-ray crystal constitution, body structure, and enzyme mechanisms.

Under the able and certified editorial management of Dr. Gerald Litwack, Vitamins and Hormones maintains to post state-of-the-art studies of curiosity to endocrinologists, biochemists, nutritionists, pharmacologists, mobile biologists, and molecular biologists. Others attracted to the constitution and serve as of biologically lively molecules like hormones and supplementations will, as continuously, flip to this sequence for accomplished stories via major individuals to this and comparable disciplines.

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A novel action of activin A: Stimulation of insulin secretion in rat pancreatic islets. Biochem. Biophys. Res. Commun. 156, 335–339. , Sawchenko, P. , and Vale, W. W. (1996). Molecular cloning of a novel type I receptor serine/threonine kinase for the TGF beta superfamily from rat brain. Mol. Cell. Neurosci. 7, 467–478. , and Sugino, H. (2004). Activin isoforms signal through type I receptor serine/threonine kinase ALK7. Mol. Cell. Endocrinol. 220, 59–65. , and Inokuchi, K. (2009). Activin signaling as an emerging target for therapeutic interventions.

Chem. 280, 11887–11894. Zuniga, J. , Groppe, J. , Hinck, C. , Pakhomova, O. , and Hinck, A. P. (2005). Assembly of TbetaRI:TbetaRII:TGFbeta ternary complex in vitro with receptor extracellular domains is cooperative and isoform-dependent. J. Mol. Biol. 354, 1052–1068. C H A P T E R T W O Crystal Structure of Activin Receptor Type IIB Kinase Domain Seungil Han Contents I. Introduction II. Type I Receptor Kinase Domain Structures A. TGF-b RI kinase domain structure B. ActRIA structure in complex with FKPB12 and dorsomorphin III.

And Bradley, A. (1995). Functional analysis of activins during mammalian development. Nature 374, 354–356. , and Gurdon, J. B. (1999). Activin as a morphogen in Xenopus mesoderm induction. Semin. Cell Dev. Biol. 10, 311–317. , and Cerasi, E. (1993). Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters. Proc. Natl. Acad. Sci. USA 90, 3865–3869. , and Cerasi, E. (2002). Regulation of insulin gene transcription. Diabetologia 45, 309–326.

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